The Key Discipline of Shandong Province Biochemistry and Molecular Biology

2016-05-20 11:28     School of Life Sciences        

The discipline of Biochemistry and Molecular Biology was established in May 2003, and rated as a key subject in Shandong Province in November 2006. Currently it has 38 research staff, including 11 professors, 16 associate professors, and 11 lecturers.

Research Directions

Plant Molecular Biology

Mainly focus on the study of molecular regulation of Actin Depolymerizing Factors (ADFs) in plant cell shape maintenance and cell elongation; the regulatory functions of nuclear pore proteins and RNA helicase in mRNA nuclear-cytoplasmic transport and plant stress resistance; and the molecular regulation of ethylene receptors and signaling. The researchers of the group also conduct the study on soybean SNP molecular markers and high throughput transcriptome profiling and analysis. And, the molecular markers have been applied in the construction of molecular linkage genetic map and the functional study of crops’ important agronomic traits. The research projects have achieved significant progress and provide new genetic resources for molecular breeding of crops.

Plant Physiology and Biochemistry

Include the research on signal transduction pathways of nitric oxide, ethylene, jasmonic acid and salicylic acid; the regulation of stomatal movement; and the physiological and biochemical basis of plant stress resistance in grape, tobacco, wheat, etc. The researchers also conduct the physiological and biochemical studies of different bryophyte in absorbing environmental heavy metal pollution and drought tolerance. Using gene chip assay, 2-D electrophoresis and MSAP technique, some researchers from the group work on the regulation of peony internal dormancy in flowering at the level of genetics and epigenetics. By extracting and separating active substances from peony petals and stamens, the researchers analyze the pharmacological functions of the active contents in peony plant.

Plant Gene and Cell Engineering

group researchers are mainly engaged in discovering and marking high quality resistant gene in crops, such as peanuts, beans and tomatoes. Using high-tech methods such as simulated aerospace mutagenesis, high energy particle field mutagenesis, and chemical-induced mutagenesis, combined with plant tissue culture, the researchers aim to create new peanut germ lines, isolate and identify antiviral genes in tomato and maize, map and clone the tomato third chromosome genes.

Scientific Research Funding

In recent years, the research groups from the key discipline of Biochemistry and Molecular Biology have undertaken over 50 research projects, including 16 of National Natural Science Foundation, 9 of Shandong province Natural Science Foundation, 7 projects from the Science and Education departments of Shandong province, 5 projects of other provincial, 5 subjects from Qingdao government, and 10 from companies. Total research funding is over 20 millions.

Symbolic Achievements

The research groups from the key discipline of Biochemistry and Molecular Biology have received 7 national and provincial awards, and published over 200 research papers, most of them have been recorded by SCI or EI. Over 30 national invention patents have been granted. And, the achievements of technology transfer and application from the research groups have created direct economic benefits over 400 million yuan in past years.

 

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